Abstract
BackgroundCerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis. Isolated cerebellar cortical vein thrombosis is a very rare phenomenon.Case presentationThis report describes a case with CVT, which is manifested as space-occupying lesions of the cerebellar hemisphere and mimics a cerebellar tumor at the beginning. The diagnosis of CVT was finalized given the laboratory and brain biopsy findings. The etiology may be related to polycythemia vera with Janus Kinase 2 V617F mutation.ConclusionIsolated cerebellar vein thrombosis should be considered when swelling and enhancing cerebellar lesions are detected. Polycythemia vera, especially with a positive JAK2 V617F mutation, may be a rare risk factor for CVT.
Highlights
Cerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis
Cerebral venous thrombosis (CVT) is a cerebrovascular disorder. It is associated with the occlusion of dural sinuses and cerebral veins and results from the blocked cerebral venous reflux, usually causing non-hemorrhagic and hemorrhagic stroke and being a serious, even potentially life-threatening, disease. [1, 2] CVT is a rare condition and represents approximately 1–4% of all intracranial vein thrombosis [1, 2]
The patient was diagnosed with Polycythemia vera (PV) by bone marrow biopsy via PCR detection four years prior to presentation and received long-term
Summary
Isolated cerebellar vein thrombosis should be considered when swelling and enhancing cerebellar lesions are detected.
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