Abstract
Aspergillus sp. is a fungus that is very common in nature and may cause invasive disease with high mortality, especially in immunosuppressed patients. Here we present a case of central nervous system (CNS) aspergillosis in a previously healthy immunocompetent patient. A 23-year-old female was admitted to hospital with the complaints of headache, blurred vision, and double vision. In her cranial magnetic resonance imaging, abscess and paranchymal edema were observed in the left frontal lobe, and biopsy was performed with endoscopic nasal operation. The pathology result was consistent with aspergillus infection. It should be remembered that although CNS aspergillosis generally occurs in immunosuppressed patients, it may also rarely be diagnosed in immunocompetent individuals.
Highlights
Aspergillus sp. is a fungus that is very common in nature and may cause an invasive disease with high case fatality rate, especially in immunosuppressive patients [1]
Fungal infections of the central nervous system mostly result from systemic circulation secondary to lung infection, and may result from the direct extension
A study performed by Murthy et al reported that central nervous system aspergillosis resulted from the direct extension from the paranasal sinuses in 76% of cases [8]
Summary
Aspergillus sp. is a fungus that is very common in nature and may cause an invasive disease with high case fatality rate, especially in immunosuppressive patients [1]. Is a fungus that is very common in nature and may cause an invasive disease with high case fatality rate, especially in immunosuppressive patients [1]. Major risk factors for aspergillus infection include neutropenia and corticosteroid use [2]. Central nervous system (CNS) aspergillus is very rare in immunocompetent patients.
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