Abstract
Central osseous tumors, which are radiographically multilocular and have multinucleated giant cells microscopically, present the surgeon and the pathologist with a diagnostic dilemma. In the case presented here the histologic diagnosis of central giant cell granuloma conflicts with the presentation of an atypical case of cherubism. Central giant cell granuloma and cherubism are discussed briefly, and the necessity of basing the final diagnosis on clinical presentation is demonstrated.
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