Abstract
AbstractOut of 92 medical students, five success‐motivated and five failure‐motivated subjects were selected for a study of the central effects of nifedipine. In a cross‐over design and under double‐blind conditions, the subjects were administered 10 mg nifedipine or placebo twice daily over a five‐day period. A general evaluation of the results did not reveal any influence of nifedipine on vigilance (CFF), detail discrimination capacity (d2‐test), responsiveness (tracking test), and subjective feelings. However, success‐motivated and emotionally stable subjects were markedly impaired by nifedipine (CFF and d2‐test, quantitative performance), whereas failure‐motivated, emotionally unstable and introverted subjects under nifedipine exhibited less errors in the tests (d2‐test, qualitative performance) compared to those who were given placebo.
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