Abstract

Airborne particulate matter has been linked to neurodegeneration in recent epidemiological studies. Previous work in our lab has shown that different types of particulate matter elicit different reactions. We set out to investigate two different particulate matter types in microglial cells to see whether they would have the same effect in different types of neurological cells. We combined caspase‐3 assay with lipid profiling to determine the mode of cell death induced by several different types of airborne particulate matter. Some types of particulate matter induced cell death via apoptosis and others induced cell death by neuroinflammatory methods.Support or Funding InformationNIH P20GM103443

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