Abstract
A 40-year-old female, previously healthy, started 2 months earlier with skin lesions (Figure 1A) characterized by blisters of 3 to 4 cm on the trunk and extremities that, when broken, left denuded areas, excoriations, and painful and pruritic meliceric crusts with serohematic secretion: with involvement of the gingival mucosa, palate, and oropharynx. Biopsy is performed (Figure 1B) showing intraepidermal acanthosis in the lower portions of the epidermis and spongiosis with exocytosis of neutrophils, perivascular infiltrate with eosinophils in the dermis. Human Immunodeficiency Virus (HIV) positive is reported by Elisa. At the respiratory level, he progressed with respiratory acidosis, for which a chest X-ray was taken (Figure 1C) with an increase in the parahilar pattern, with no evidence of a pneumonic process.
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