Catalytic hydrogenation of the C=N bond 4. Hydrogenation of azomethines containing a p-dimethylamine substituent

Abstract

1. A study has been made of the hydrogenation of azomethines with p-dimethylamino groups in the amine and aldehyde rings, working in ethanol solutions containing 5% Pd/C. 2. The alteration in the hydrogenation kinetic parameters under substitution is the result of p-N(CH3)2 group interaction, with the C=N bond rather than with the catalyst. 3. Although introduction of a p-dimethylamino group into the amine ring of the azomethine has little effect on the hydrogenation kinetic parameters, introduction of this same group into the aldehyde ring markedly reduce both the activation energy and the reaction rate.