Abstract
The stability of the heterogeneous CuHY catalyst for the aziridination of styrene using nitrene donors, with and without the presence of chiral bis(oxazoline) modifiers, is described in detail. Cu2+ is found to leach from the CuHY and the rate of Cu-leaching is dependent on the reaction time, the nature of the nitrene donor, the structure of the bis(oxazoline), the presence of solvent and the breakdown products of the nitrene donor. It is found that between 0.08–6.8% by weight of the Cu present in CuHY can be leached during standard reaction conditions. However, using short reaction times it is shown that the amount of Cu removed can be limited readily to the lower value. Detailed studies show that for this reaction system the leached Cu2+ plays no significant role in the formation of the aziridine, and that the high enantioselectivities observed with CuHY are due to Cu2+ which is electrostatically bound within the pores of the zeolite and modified by a chiral bis(oxazoline) ligand.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Perkin Transactions 2
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
