Abstract

Presentation of Case A 56-year-old woman was admitted to the hospital because of recurrent intermittent fever after renal transplantation. There was a history of interstitial nephritis that led to chronic renal failure six years earlier. Extracorporeal hemodialysis was begun. Three months before entry a cadaveric renal-transplantation procedure was performed. The patient's postoperative course was complicated by fever, with the temperature rising as high as 38.9°C on the seventh postoperative day. A diagnosis of acute rejection was made. Management of her care included three 500-mg boluses of methylprednisolone by vein and a 12-day course of OKT3 monoclonal antibodies; ganciclovir was administered . . .

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