Abstract
Diabetes mellitusis a chronic hyperglycemia associated with elevated plasma cholesterol.Natural and traditional herbal remedies are a source of new commercial products. Anti-diabetic potential of D. mucronata extracts (methanol) has been assessed in alloxan monohydrate diabetic induced rabbits.The extracts were given orally by 8 hours. Thedose rate was 12 mg, 125mg, 225 mg and 325mg/kg body weight respectively.At every 2 hours blood sample was collected, serum separated and glucose level was determined by kit method. The result suggests that the treatment of 325 mg/kg body weight significantly(p<0.05) decreased blood glucose and cholesterol level at 143 mg/dl and 166.33 mg/dl in the experimental group.Therefore, it is concluded that the D. mucronata possess significant anti-diabetic activity.
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