Abstract
The negative prognostic importance of diabetes mellitus (DM) on cardiovascular outcomes is well known. DM is considered as coronary artery disease (CAD) equivalent, which places an asymptomatic individual with DM in the high-risk group. Direct coronary imaging of CAD in asymptomatic high-risk individuals is controversial. In particular, the role of non-invasive cardiac computed tomography (CCT) in asymptomatic diabetics is less well understood.1–6 In this issue of the Journal, Kim et al. 6 shed light on this topic with the results of the CRONOS-ADM prospective registry (CoROnary CT aNgiography evaluation for clinical OutcomeS in Asymptomatic patients with type 2 Diabetes Mellitus). These data provide insight into several aspects of the DM relationship with time and CAD extent using CCT in an asymptomatic population of individuals. The relevant findings of the study are that DM duration is associated with progression in the extent and severity of CAD which independently predicts an increased risk of major adverse …
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