Abstract
Determination of death, the exact moment that a person’s death occurs, has been a constant challenge throughout human being history. What we already know is that death usually does not occur abruptly, at a specific time and for all parts of the body simultaneously. Human resistance to degradation by lack of oxygen varies depending on the type of cell and organ. It is possible, for example, for successful cornea transplants from deceased individuals as many as seven days after death. Actually, the absolute absence of any residual vital activity in the body after cessation of circulatory function, can only be confirmed once the putrefaction process is fully established and completely widespread throughout the corpse. It is not feasible logically, however, to wait until that point to declare death, due to safety and public health reasons.
Highlights
Another obvious reason to of life of certain patients, thanks to organ donation and transplantation processes [1]
The laws of a large number of countries around the world support the determination of death of an individual in the clinical setting according to two alternative conditions [3]: After declaring the irreversible cessation of cardiorespiratory functions, or
Thanks to cardiopulmonary resuscitation (CPR), certain patients suffering cardiac arrest are reversed from the episode, and if ensured adequate perfusion of the brain during the process, reducing the so called no
Summary
Another obvious reason to of life of certain patients, thanks to organ donation and transplantation processes [1]. On the one hand, harvesting vital organs from living people, causing their death, is currently unacceptable worldwide [2] but, on the other hand, waiting too long after declaring death to begin the organ extraction could compromise the quality and quantity of organs retrieved and declare the death of an individual as soon as possible is the possibility of saving lives or improving the quality and outcomes in terms of long term graft and recipient survival Both theoretical and practical problems of determination of death in the context of organ donation are rooted in this kind of tug of war game between obtaining organs in optimum conditions without affecting the goal of providing quality care at the end-of-life stage for potential donors, still patients. In such cases brain function does not exist, and the patient is declared legally dead, but simultaneous loss of circulatory function does not occur These so called heart-beating deceased donors can provide an important quantity of organs. What is the status of their cognitive functions, their brain function, along the process of preservation and retrieval of vital organs for transplantation?
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