Abstract
Objectives To evaluate carbonyl groups (CG) serum levels in B-chronic lymphocytic leukemia (B-CLL) patients. Design and methods CG serum levels were assessed in 48 B-CLL patients and in 30 control subjects. Results CG were increased in B-CLL patients. We found a positive correlation between CG with CD38 expression and a negative correlation with ZAP 70 expression. Conclusions B-CLL patients displayed an unbalance of the oxidative stress. CG serum levels could be considered as a prognostic factor in B-CLL.
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