Abstract
The onset of ventricular depolarization defines the start of the pre-ejection period (PEP), which is commonly used as an index of myocardial contractility. Although the fiducial point for this onset has traditionally been the onset of the Q wave of the electrocardiogram (qPEP), the Q wave is not visible in some patients. Therefore, other measurement points have also been used in the literature, including the peak of the R wave (rPEP). However, there has been little systematic examination of measurement issues associated with the selection of the fiducial point for ventricular activation.
Highlights
The onset of ventricular depolarization defines the start of the pre-ejection period (PEP), which is commonly used as an index of myocardial contractility
The aim of this study is to evaluate rPEP for detecting the left ventricular contraction performance compared with qPEP
After approval of the institutional animal ethics, six adult pigs weighting 40kg were anesthetized with an i.m. injection of ketamine, midazolam and atropine sulfate
Summary
The onset of ventricular depolarization defines the start of the pre-ejection period (PEP), which is commonly used as an index of myocardial contractility. Objectives The aim of this study is to evaluate rPEP for detecting the left ventricular contraction performance (dp/dt) compared with qPEP. Methods After approval of the institutional animal ethics, six adult pigs weighting 40kg were anesthetized with an i.m. injection of ketamine, midazolam and atropine sulfate.
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