Abstract
In this issue of EMBO Molecular Medicine, Stebbing etal (2020b) validate an artificial intelligence-assisted prediction that a drug used to treat rheumatoid arthritis could be a potent weapon against COVID-19. Using liver organoids infected with SARS-CoV-2, they confirm dual antiviral and anti-inflammatory activities and show thatits administration in four COVID-19 patients is correlated with disease improvement, paving the way for more rigorous placebo-controlled trials.
Highlights
In this issue of EMBO Molecular Medicine, Stebbing et al (2020b) validate an artificial intelligence-assisted prediction that a drug used to treat rheumatoid arthritis could be a potent weapon against COVID-19
S evere COVID-19 cases are associated with hyperactivation of the immune system, which can lead to acute respiratory distress syndrome, other secondary immune disorders, and death (Mehta et al, 2020)
A drug that combines antiviral and immunosuppressant activities could be a powerful treatment (Perricone et al, 2020). In this issue of EMBO Molecular Medicine, Stebbing et al (2020b) test the prediction that an anti-inflammatory molecule used for rheumatoid arthritis (RA) has antiviral activity and could improve the outcomes of those afflicted by severe COVID-19 (Fig 1)
Summary
In this issue of EMBO Molecular Medicine, Stebbing et al (2020b) validate an artificial intelligence-assisted prediction that a drug used to treat rheumatoid arthritis could be a potent weapon against COVID-19. A drug that combines antiviral and immunosuppressant activities could be a powerful treatment (Perricone et al, 2020). In this issue of EMBO Molecular Medicine, Stebbing et al (2020b) test the prediction that an anti-inflammatory molecule used for rheumatoid arthritis (RA) has antiviral activity and could improve the outcomes of those afflicted by severe COVID-19 (Fig 1).
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