Abstract
Moro and colleagues should be commended for their recent article in Annals of Neurology on deep brain stimulation (DBS) for Huntington’s disease, the latest contribution to their ongoing effort to use constant energy paradigms to optimize DBS parameters and to determine which parameters have the most impact on clinical outcomes. An important measure of optimization is that which the authors term total electrical energy delivered or TEED. TEED, the total energy delivered by an electrical system over an arbitrary period of time, is determined by the programmed parameters of stimulation and the measured system impedance. In theory, optimized DBS settings will generate maximal clinical benefit at the lowest possible TEED, resulting in fewer stimulationrelated complications and longer battery life. The authors report that they use the following equation to calculate TEED:
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