Abstract
The present study analyzed the in vivo effects of drinking caffeinated and decaffeinated instant coffee (8% w/v) by adult male Wistar rats submitted to high-intensity exercises. The parameters used in the evaluation were the determination of the activities of NADPH oxidase, myeloperoxidase and other antioxidant enzymes present in neutrophils of rats. It was observed that exercise-induced superoxide anion production depends on the NADPH oxidase activity (estimated by the cytochrome C reduction test) in peritoneal neutrophils (p < 0.05). The intake of caffeinated and decaffeinated instant coffee beverages and of a caffeine solution to 1.67% did not induced changes in myeloperoxidase, superoxide dismutase and glutathione peroxidase activities in the peritoneal neutrophils of rats after exercise (p < 0.05). From the obtained results, it was concluded that moderate intake of caffeinated instant coffee (equivalent to a daily human consumption of 4 50-mL cups of coffee) may have beneficial effects on health, contributing to a reduction in superoxide anion generation triggered in neutrophils after high-intensity exercise.
Highlights
Coffee is currently recognized as a super functional food, a fact that adds value to the traditional consumption of the beverage by people of all social classes, including athletes
The rats were divided into 8 groups containing 8 animals in each: animals group not subjected to intense exercise and treated with water; animals group subjected to intense exercise and treated with water (Exer); animals received caffeinated instant coffee and not subjected to intense exercise (CC); animals received decaffeinated instant coffee and not subjected to intense exercise (CD); animals treated with caffeine solution and not subjected to intense exercise (CF); animals treated with caffeinated instant coffee and subjected to intense exercise (Exer.CC); animals treated with decaffeinated instant coffee and subjected to intense exercise (Exer.CD); and animals treated with caffeine solution and subjected to intense exercise (Exer.CF)
Caffeinated instant coffee prevents an increase in exercise-mediated superoxide anion production in rat peritoneal neutrophils produced in high concentration are responsible for an increase in oxidative stress markers, such as lipid peroxidation, protein carbonylation and DNA mutations that result in decreased muscle strength and muscle fatigue (Kawaura et al, 2018)
Summary
Coffee is currently recognized as a super functional food, a fact that adds value to the traditional consumption of the beverage by people of all social classes, including athletes. Conflicts of interest: The authors have no conflict of interest to declare.
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