Abstract
Wendy Young has a distinct memory of the first time she played the flute with a full orchestra. She was just a fifth-grader but recalls the thrill of the music surrounding her. “It just fills you,” Young says. “Your one sound goes with 200 people. I remember I couldn’t sleep that night being part of something bigger.” She gets that same feeling about drug discovery. As with music, her talent for organic chemistry was evident early on; visualizing chemical structures and imagining how a synthesis could unfold came easily. But the real excitement comes when those skills are put to work alongside other talented scientists. That’s when new medicines get made. Young joined Genentech in 2006, a time when the historically antibody-focused firm was trying to establish equal expertise in small molecules. Michael Varney, who now leads R&D at Genentech, had championed bringing her into the fold, and she started
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