Abstract
If anybody knows what types of drug candidates or research methodologies are likely to be successful, it should be Ge Li, the founder and chief executive officer of WuXi AppTec. The world’s largest contract research organization, or CRO, WuXi employs 10,000 people who work on behalf of 2,000 customers worldwide, ranging from virtual drug discovery firms to the world’s largest pharmaceutical makers. Yet despite his company’s work on thousands of research programs every year, Li claims no particular insight on what will yield a commercial drug. “We don’t have a crystal ball to know that this or that program will be successful,” Li says. “If everyone starts focusing on one target, it doesn’t mean that this target will work.” At most, he says, WuXi has an idea of what targets and methodologies are popular among researchers. Others in the drug industry would say Li is being modest. Considering WuXi’s vast
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