By the rivers of Babylon: the 1889-cholera outbreak in Iraq, production of medical knowledge, and construction of scientific periphery

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By examining the 1889 cholera outbreak in the Iraqi Ottoman provinces, this article explores the global dynamics of medical knowledge production at the turn of the nineteenth century. While the 1892-1893 outbreak is typically viewed as a pivotal moment in the history of cholera with the triumph of germ theory, this study investigates an earlier epidemic to analyze both the transformation of medical understanding and the complex knowledge exchanges between Western and Eastern scientific communities. The article critically examines the hierarchical structures that mediated scientific communication, revealing how established power dynamics shaped the circulation of medical knowledge. By examining these intellectual networks this article demonstrates how contemporary scientific discourse constructed and reinforced the concept of scientific periphery. By doing so, this study seeks to integrate Baghdad into broader narratives of global medical history and scientific knowledge production.

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This paper is focused on the production and circulation of medical knowledge ‘from below’ in the early stages of the COVID-19 pandemic. Specifically, the aim is to investigate the link between personal and professional resilience and the sharing of knowledge and practices at a time of epistemic rupture. The empirical case intends to discuss a Community of Practice (CoP) formed by a network of health professionals spontaneously activated in northern Italy during the first pandemic waves. Dynamics within the network were examined through a grounded theory approach, bringing out some analytical categories from the empirical field – 18 video interviews. Emerging narratives within the CoP reaffirm the value of medical practice, highlighting how in a condition of structural crisis expertise can give meaning to individual action through shared processes of signification, filling the temporary absence of recognized and established knowledge: recognizing the relevance of CoPs in knowledge production and circulation could better integrate them into the healthcare organization to promote systemic change and sustainability.

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  • 10.2307/3527849
The SUPPORT Study: Who's Talking?
  • Nov 1, 1995
  • The Hastings Center Report
  • Patricia A Marshall

In recent years, the public has become increasingly concerned about the use of medical technologies and pain management for seriously or terminally ill patients. The process of death and dying, particularly a hospital setting, is often characterized by feelings of abandonment and loss of control on the part of patients and their families. Efforts to legalize physician-assisted suicide California and Washington, and the success of the referendum Oregon, reflect the public's overwhelming dissatisfaction with what is perceived as physicians' unwillingness to recognize the suffering experienced by terminally ill individuals. Moreover, health professionals, legislators, and patients alike have expressed discontent with the high cost of end-of-life medical care. Taken together, these considerations suggest that innovative attempts to reform health care for the seriously and terminally ill are long overdue. The SUPPORT study represents a major effort this direction. The size and scope of this multisite study make it historically unique. A primary goal of SUPPORT was the development of a model intervention that would enhance the frequency and effectiveness of patient-physician communication about medical decisions. Yet patient care remained unchanged. The SUPPORT intervention's inability to produce any modification patient care illustrates profoundly the force and tenacity of Western biomedical culture. In matters of end-of-life decisionmaking, the production and application of medical knowledge reveal deep-seated values and beliefs about patient-physician relationships, control the practice of biomedicine, and the nature of human mortality. At its core, end-of-life decisionmaking a hospital setting rests on a set of tacit assumptions about biomedical reality that strongly influence the process and experience of death and dying. Power and Control Medical Practice Legitimation of authority biomedicine is expressed and reinforced through a hierarchy of social dominance. Central to this issue of authority are questions surrounding the creation and production of medical knowledge. When end-of-life decisions must be made, who determines what medical data have significance, what information is relevant and whose voices may be heard? Traditionally it is physicians who have held the reins deciding the substance and parameters of medical decisionmaking. Although current developments the reorganization of health care practice toward managed care and managed competition may result fundamental changes the balance of medical power, the conventional authority of physicians as the creators of biomedical knowledge is likely to remain strong. Patients, their surrogates, physicians, and nurses all participated actively Phase II, the experimental stage of the SUPPORT project. However, responsibility for implementing the interventions designed for SUPPORT rested heavily on the nurses. It was the nurse who spoke initially with a patient about his or her concerns and desires for medical treatment; it was the nurse who became the conduit of information about a patient's treatment preferences and prognostic status. To a certain extent, this means business as usual a medical environment where typically nurses are relied upon to talk to patients and their families and relay messages to physicians in charge. In the context of biomedical and social power, perhaps the supplemental knowledge generated by the nurses concerning advance care planning for end-of-life decisionmaking was contained an all too familiar package. The SUPPORT intervention yielded important information about patients and provided opportunities for that knowledge to be used and acted upon. Unfortunately, this production of knowledge replicated the historical pathways of patient care. Do physicians read the nursing notes patient charts or listen to nurses' requests on behalf of patients? If the physician reads the chart or discusses the issues with nurses, is the material taken seriouly? …

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On Slavery, Medicine, Speculation, and the Archive
  • Feb 1, 2023
  • Historical Studies in the Natural Sciences
  • Elise A Mitchell

In 1777, word spread along the Amazonian coast that the “cruel contagion of smallpox” was circulating in the Portuguese frontier captaincies of Grão-Pará and Maranhão.1 Rumor often announced the arrival of smallpox before authorities.2 The rumors wound their way along the roads and waterways of Belém, the capital of Grão-Pará, to the ears of thirty-three enslaved Africans, all of them property of Chief Physician Bento Viera Gomes. They were terrified of the ongoing outbreak—and of their enslaver. They knew of Gomes’s attempts to prevent the spread of smallpox by inoculating a group of soldiers stationed nearby. The soldiers refused the inoculations, fearing the disease and the procedure.3 To prove the procedure was safe and effective, Gomes conscripted the thirty-three to serve in an inoculation demonstration for the soldiers. As Gomes remarked, the enslaved people “(although equally fearful)…had no choice but to obey.”4 Each of them, between the ages of three and twenty-five, underwent the procedure. All survived. Nevertheless, this brief chapter in the history of inoculation brings questions of survival, quality of life, and archival objectivity to the fore.The slave trade and slavery established power relations that shaped the terms of scientific and medical knowledge production and practice. European imperial and medical archives naturalize these power relations. It is the historian’s task to unsettle and expose them. The intellectual foundations that presuppose inoculation as an inherent good because it saved lives (and it certainly did) do not prioritize Black people’s healing and well-being. To do so requires affective labor that begins with archival critique and proceeds with speculation.We find this inoculation story buried in a flurry of accounts from medical practitioners around the Portuguese-American colonies discussing plans for the implementation of the Jennerian cowpox vaccine.5 As a show of expertise to the Crown, physicians like Gomes highlighted their prior experiences using inoculation and demonstrated their knowledge of the literature, citing works such as Thomas Dimsdale’s recently translated inoculation manual.6 Vague allusions to inoculations performed in the British colonies, the primary competition for Amazonian industries, also pepper the pages. Perhaps Gomes read the Letters and Essays published by the notorious physician John Quier who experimented with smallpox inoculation on young, pregnant, and elderly enslaved Africans in Jamaica.7Too often, the history of inoculation serves as a prelude to triumphalist narratives of the resounding success of the Jennerian vaccine. Yet in the archival record, undercurrents of exploitation are plain: “they had no choice but to obey.” Enslaved people were the ideal candidates for inoculation demonstrations because colonists and slaveowners viewed them as replaceable commodities, chattels, and units of labor.8 They were expendable, yet essential to the imperial project.9 In Grão-Pará, inoculation would enable the imperial project to proceed despite its health consequences. Most enslaved people survived smallpox outbreaks or inoculation only to die of other causes. Even lifesaving technical and medical advancements can work to maintain the social, environmental, and existential order. Rather than sustaining life, smallpox inoculation reproduced and maintained the intertwined systems of imperialism and slavery, with their violence, pernicious inequity, morbidity, and needless death.Perhaps we might imagine beyond the thirty-three enslaved Africans’ fears and their enslavers’ reputed successes, through wonder, speculation, and questions.10 How much care and tenderness persisted amid the violence? Did parents or siblings hold the three-year-old as they prepared to receive an inoculation? Were mothers forced to hand over their children to strangers in the process? Did they smell the infected, who braced themselves to have smallpox pus removed? Did the infected person look at the recipient reassuringly? Did they exchange words, prayers, hopes, or ask questions about the procedure? Perhaps the twenty-five-year-old assisted, hoisting the small children into their lap and calming them before the incision. 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The traditional researcher-driven environment of medical knowledge production is losing its dominance with the expansion of, for instance, community-based participatory or participant-led medical research. Over the past few decades, sociologists of science have debated a shift in the production of knowledge from traditional discipline-based (Mode 1) to more socially embedded and transdisciplinary frameworks (Mode 2). Recently, scholars have tried to show the relevance of Mode 2 knowledge production to medical research. However, the existing literature lacks detailed clarifications on how a model of Mode 2 knowledge production can be constructed in the context of medical research. This paper calls for such further clarifications. As a heuristic means, the advocacy for a controversial experimental stem cell therapy (Stamina) is examined. It is discussed that the example cannot be considered a step towards Mode 2 medical knowledge production. Nonetheless, the example brings to the fore some complexities of medical knowledge production that need to be further examined including: (1) the shifting landscape of defining and addressing vulnerability of research participants, (2) the emerging overlap between research and practice, and (3) public health implications of revising the standard notions of quality control and accountability.

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Innovation Policy and the Economy
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The fifteenth volume of Innovation Policy and the Economy is the first to focus on a single theme: high-skilled immigration to the United States. The first paper is the product of a long-term research effort on the impact of immigration to the United States of Russian mathematicians beginning around 1990 as the Soviet Union collapsed. The second paper describes how obtaining a degree from a US undergraduate university can open an important pathway for immigrants to participate in the US labor market in IT occupations. The third paper considers the changing nature of postdoctoral positions in science departments, which are disproportionately held by immigrant researchers. The fourth paper considers the role of US firms in high-skilled immigration. The last paper describes how strong growth in global scientific and technological knowledge production has reduced the share of world scientific activity in the United States, increased the immigrant proportion of scientists and engineers at US universities and firms, and fostered cross-border collaborations for US scientists.

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  • 10.1515/multi-2022-0034
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  • Jan 1, 2019
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  • Research Article
  • Cite Count Icon 2
  • 10.7867/1809-0354.2007v2n3p444-460
PRODUÇÃO DE CONHECIMENTO NO CONTEXTO BRASILEIRO: PERSPECTIVAS DE INSTITUIÇÕES EMERGENTES
  • Jan 1, 2007
  • Stela Maria Meneghel + 3 more

Worldwide, the production of scientific knowledge (or simply search) has increased exponentially in recent decades. In Brazil, this increase has occurred, mainly, because of the creation of new programs for post-graduate (masters and doctorate) in scientific journals. However, it has not been even and universities in different regions of the country: it is concentrated in centres of excellence. This text seeks to characterize the differences in scientific production centres of excellence as opposed to other types of institutions, called peripheral and emerging. Thus, the principle considers the origin of these terms in Economics and Geography and its translation into other areas of knowledge. Then, with support in terms of concepts about 'know-how' and 'time to do' search, featuring Postgraduate Programs and universities as centers of excellence, peripheral and emerging. In sequence, indicates the limitations of the institutions and emerging Post-graduate programs to achieve scientific parameters of reference (data by financing agencies) that focus the international insertion of the search. Thus, shows that the emerging universities, as they take care of issues unrelated to their surroundings closest (to obtain resources of the agencies), tend to lose the opportunity to contribute in the resolution of local demands of regional development. This study, based on bibliographic data, concludes with considerations about the difficulty of measuring the social commitment of scientific production, debating the need to rethink criteria for the evaluation of financing agencies and establish ways to measure its impact on society, and policies for funding stimulate the production of knowledge with local insertion. Keywords: Emerging Universities; Peripheral Universities; Production of Knowledge; Regional Development.

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  • Isis
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This essay considers the creation of a gender identity clinic at Rikshospitalet, the National Hospital of Norway, in the early 2000s and its implications for the production of medical knowledge during that era. In the preceding decades, medical transition was overseen by an informal, self-organized, multidisciplinary team of medical experts, but this situation changed when a centralized gender identity clinic was established under psychiatric control. The essay argues that shifting institutional, societal, economic, legal, and bureaucratic circumstances redistributed expertise and authority on trans medicine. Economic framing, institutional frictions, patient activism, and media attention restricted the doctors’ room for maneuver and created a scientific crisis of legitimacy in trans medicine. These processes changed medical knowledge regarding medical transition; eventually, “sex change” and, therefore, all that is denoted by “sex” became intertwined with and inseparable from the politico-bureaucratic processes of reforming a modern public health-care system and welfare state. By anchoring the analysis in the history of science and expertise, this inquiry offers a new focus on the role of bureaucratic practices in the production, structuring, and circulation of medical knowledge in the welfare state.

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