Abstract
BackgroundThe body fat reduction has been a major health goal of obese individuals throughout the world and identifying functional foods that can assist in alleviatingthe excess body fat has been the objective of various studies. ObjectiveThe current study was investigated to evaluate the anti-obesity profile of Butea monosperma (BM) flower extract on the high-fat diet (HFD) induced obese rats. Material & methodsCD and AD diet was fed for 40 days to induce obesity in Female albino rats. Three different doses of BM flower extract (100, 200 and 400 mg/kg, per oral) were administered every day to the drug treatment groups. The observations were made for body weight measured at every 5 day interval, various organs and body fat pad weights, body temperature, locomotor activities along with total cholesterol, triglyceridesand glucose levels were analyzed on the 39th and 40th day. ResultBM flower extract 400 mg/kg (high dose) treated rats showed a significant decrease in body weight, total cholesterol, triglycerides levels, and glucose levels with marked elevation in locomotor activities and body temperatures. ConclusionThe findings suggests that the supplemented BM flower extract in the CD and AD have normalized the weight gain parameters and can be a future herbal candidate for reversing obese individual to normal.
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