Abstract
Maiman's discovery of the laser in 1960<sup>1</sup>led to many technical advances. Field use of lasers has become widespread, and medical institutions are installing laser devices for clinical or research use. As the use of high-power lasers, particularly those that function continuously, becomes more extensive, accidental or intentional exposure will, of course, increase. The possibility of detrimental effects as a result of such exposures is a serious hazard. Recently, considerable work has been done with continuous wave (CW) gas lasers containing carbon dioxide and nitrogen. Relatively high power has been achieved with these devices; continuous power output exceeding 2,500 ws has been reported, and much higher outputs are within the present state of the art.<sup>2</sup>These potential hazards prompted us to study the biologic effects of exposure of living animals to CO<sub>2</sub>laser radiation. <h3>Unique Characteristics of the CO2 Laser</h3> The CO<sub>2</sub>gas laser possesses
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