Burden of inflammatory bowel disease in India: analysis of the Global Burden of Disease study from 1990 to 2019.

Abstract

Listen

Translate article

Inflammatory bowel disease (IBD) is increasing across the globe, more so in populous countries like India. We aimed to study the disease burden and epidemiological trends of IBD in India and look closer into the disease pattern across the country from 1990 to 2019. The burden of IBD was estimated in India using the data from the Global Burden of Disease estimate for 2019, which is a comprehensive worldwide project. The analysis included various parameters like incidence, prevalence, mortality, disability-adjusted life years, years lived with disability, and years of life lost as age-adjusted rates (per 100,000 population). Using modeling, the prediction was also made for 2050 in India. The age-standardized incidence, prevalence, mortality, and disability rates of IBD in India for 2019 were 2.34, 20.34, 0.40, and 13.04, respectively. These are lower than the global incidence, prevalence, mortality, and disability rates of 4.97, 59.25, 0.54, and 20.15, respectively. The annual rates of change in incidence, prevalence, mortality, and disability rates in India from 1990 to 2019 were 0.05, -0.02, -0.36, and -0.35, respectively. The annual rates of change in incidence and prevalence are higher than the global rate of -0.18 and -0.19, while the annual rates of change in mortality and disability are lower than the global rate of -0.19 and -0.26. The incidence and prevalence of IBD in India are lower compared to the global population but are increasing at a faster rate than the global population.