Abstract

The capability to build parts with predetermined porous microstructure and dense walls using powdered biomaterials makes selective laser sintering (SLS), one of the more flexible rapid prototyping (RP) process, a strong candidate for building biodegradable controlled release drug delivery devices (DDD). The objective is to design a varying-porosity circular disc with outer region being denser acting as diffusion barrier region and inner more porous region acting as drug encapsulation region. This is to achieve a zero-order of release over a desired duration of time in drug administration.

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