Abstract
Bronchiolitis obliterans with organizing pneumonia (BOOP) is a clinicopathologic entity. 1 Epler GR Colby TV McLoud TC Carrington CB Gaensler EA. Bronchiolitis obliterans organizing pneumonia. N Engl J Med. 1985; 312: 152-158 Crossref PubMed Scopus (862) Google Scholar It is pathologically defined as granulation tissue plugs within lumens of small airways, sometimes with complete obstruction of small airways and granulation tissues extending into alveolar ducts and alveoli. Findings such as extensive fibrosis and honeycombing, hyaline membranes, extensive fibrinous exudates, necrosis, acute inflammation, vasculitis, prominent eosinophils, and prominent granulomas should not be included. 2 Colby TV Lombard C Yousem SA Kitaichi M. Interstitial diseases. In: Atlas of pulmonary surgical pathology. WB Saunders, Philadelphia1991: 228-306 Google Scholar Above findings are nonspecific and common in various lung injuries of either definite or idiopathic etiology. Furthermore, clinical features show a subacute onset and the duration is less than 2 months in 75% of the patients. 3 Epler GR Bronchiolitis obliterans organizing pneumonia: definition and clinical features. Chest. 1992; 102: 2S-6S Abstract Full Text Full Text PDF PubMed Google Scholar
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