Abstract

A 25 year old presented with a 12-week history of a mobile breast lump. Mammography and breast ultrasound demonstrated a 3 cm mass lesion, extensive microcalcification and axillary lymphadenopathy. Core biopsies confirmed a grade 3 ductal carcinoma and high-grade ductal carcinoma in situ. Several weeks later her identical twin sister attended the family history breast cancer clinic. Clinical breast examination was normal but, despite the patient's age, it was decided to carry out a baseline mammogram. This showed widespread casting microcalcification, and core biopsies confirmed extensive high-grade ductal carcinoma in situ. When one twin has breast cancer, one-third of identical twins develop breast cancer at some time in their lives. Nonidentical twins of breast cancer patients have a much smaller risk of the disease. This suggests identical twins gain their increased risk by inheriting the same set of genes as their sister with cancer, rather than through sharing the womb or being brought up together. Where one twin develops breast cancer at an early age, the other has a high chance of doing likewise.

Highlights

  • Breast-sparing oncoplastic procedures (BSOP) offer a predictive marker guiding use of anti-oestrogen therapy, and radical new alternative to mastectomy and conventional breast- expression profiling appears to select patients more or less likely to conserving surgery in early breast cancer treatment

  • The aim was to document attitudes to male radiographers and the effect on the programme performance parameters through a postal questionnaire completed by 85.8% of a random sample of 2,000 women recently screened by BreastCheck

  • Nine per cent would not have proceeded if the radiographer was male; 17.5% agreed that ‘If there were male radiographers I would not return for another screening appointment’; and 18.3% were unsure

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Summary

Introduction

Breast-sparing oncoplastic procedures (BSOP) offer a predictive marker guiding use of anti-oestrogen therapy, and radical new alternative to mastectomy and conventional breast- expression profiling appears to select patients more or less likely to conserving surgery in early breast cancer treatment. We have compared the results of screening with analogue and digital technology over our first 2 years, in terms of recall rates, cancer detection rates and positive predictive value, and found no overall significant difference in any of these parameters. Abnormalities are graded as A, B or C at consensus by the radiologists and reporting radiographers depending upon the mammographic likelihood of cancer and biopsy This means that patients can be allocated to one of our three assessment clinics and at specific times within those clinics to facilitate workflow. Methods A retrospective analysis of all breast cancer patients with recurrence who had completed 5 years of follow-up was performed. Infection control is not routinely included in the quality assurance process of all units

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