Abstract
A, T, G, C: the alphabet code for the nucleotides that are the building blocks of life. Minor, but consequential, changes in this DNA coding can change gene function. Researchers have long sought better ways to edit the genetic code in cultured cells and laboratory organisms to silence, activate, or change targeted genes to gain a better understanding of their roles. This, in turn, could open the door to beneficial applications, from ecological to agricultural to biomedical. Over the years, several editing methods have been developed, but they have suffered from a lack of specificity, difficulty in assembling the molecular constituents, or concerns about off-target effects. Recently, accomplishments in genome editing across biological disciplines have been so remarkable that the method known as clustered regularly interspaced short palindromic repeats—or CRISPR—is Science 's 2015 Breakthrough of the Year (see p. 1456).
Highlights
Psychologists led the charge ic repeats—or CRISPR—is in research reproducibility
The 2015 advances using CRISPR that warrant this recognition have been on mul
New member of the human family was revealed from a hidden cave in South Africa tiple fronts
Summary
Several editquantum state of two widely ing methods have been develseparated particles, a prooped, but they have suffered cess called “entanglement.” Accomplishments in for midplate volcanoes such genome editing across biologas Hawaii. Psychologists led the charge ic repeats—or CRISPR—is in research reproducibility. Affirming that there is of the Year
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
