Abstract
This article addresses the Human T-lymphotropic virus (HTLV). This subject comprises the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health. HTLV-1/2 infection is a public health problem globally, and Brazil has the largest number of individuals living with the virus. HTLV-1 causes several clinical manifestations of neoplasm (adult T-cell leukemia/lymphoma) and inflammatory nature, such as HTLV-1-associated myelopathy and other manifestations such as uveitis, arthritis, and infective dermatitis. These pathologies have high morbidity and mortality and negatively impact the quality of life of infected individuals. This review includes relevant information for health authorities professionals regarding viral transmission, diagnosis, treatment, and monitoring of individuals living with HTLV-1 and 2 in Brazil.
Highlights
This article addresses the Human T-lymphotropic virus (HTLV)
The MS/SCTIE Portaria no. 23, of May 31, 2016, included the Western blot (Wb) test and the polymerase chain reaction (PCR) to confirm HTLV-1 infection among patients suspected of adult T-cell leukemia/ lymphoma (ATL) assisted by the Brazilian National Health System (SUS)[134]
Individuals with clinical manifestations compatible with HTLV-1/2 associated diseases Blood, organ, or tissue donors Organ or tissue recipients Family members and sexual partners of HTLV-1/2 carriers Individuals with suspicion or with sexually transmitted infections Individuals with bloodborne infections Pregnant women Intravenous drug users Cases of occupational exposure to blood or biological material, such as an accident with sharp material Individuals infected with Strongyloides stercoralis Individuals infected with Mycobacterium tuberculosis Individuals with leukemia or lymphoma
Summary
This article addresses the Human T-lymphotropic virus (HTLV). This subject comprises the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health. This review includes relevant information for health authorities professionals regarding viral transmission, diagnosis, treatment, and monitoring of individuals living with HTLV-1 and 2 in Brazil.
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