Abstract
Lyme borreliosis is a bacterial infection transmitted by ticks of the Ixodes genus that are infected by some members of the Borrelia burgdorferisensu lato spirochetes group. A common symptom is migratory erythema, the early rash caused by the tick bite on the skin. The disease progresses in months or even years, causing systemic symptoms that mainly affect the skin, joints, heart, and nervous system. The diagnosis is mainly based on symptoms and serology. The treatment of choice is doxycycline or beta-lactams; macrolides are an alternative. The prognosis with appropriate antibiotic treatment is favorable. Recurrent fever is a zoonosis caused by other species of Borrelia transmitted by flea and tick bites. It is characterized by a periodic fever and short febrile periods followed by a period of apyrexia. During the febrile period, spirochetes can be observed on a blood smear test. It is treated with doxycycline or penicillin and Jarisch–Herxheimer reactions are common.
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