Abstract
AbstractCarbene insertion into the C(sp2)−H bonds of internal alkenes was enabled in air by HFIP (1,1,1,3,3,3‐hexafluoro‐2‐propanol) as both the mediator and solvent through its cooperation with borane B(C6F5)3 as the catalyst. 3‐Diazooxindoles and 3‐diazoindolin‐2‐imines were amenable to work as the carbene precursors, and α‐oxo ketene dithioacetals acted as the internal alkenes at ambient temperature. The present synthetic protocol features metal‐free conditions, diverse substituent tolerance, and 47–84% yields, offering an efficient route to 3‐vinylated oxindole and indole derivatives.magnified image
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