Bone Mineral Density According To Mobility In Children With Osteogenesis Imperfecta

Abstract

PURPOSE: Bone Mineral Density According To Mobility In Children With Osteogenesis Imperfect. METHODS: Sample consisted of 8 children of both sexes, 8.2 ± 1.3 years-old, with osteogenesis imperfecta (Type I to IV), body weight:(24.0 ± 7.9 kg; body height: 116.9 ± 14.1 cm; cycles of intravenous pamidronate therapy:(7.2 ± 4.9; and Light Weekly Physical Activity: 55,0 ± 32,7 METs. Those patients were treated at Santa Casa Medical School. Physical activity was determined through a questionnaire [Barros et al, 1993], and CIF:CJ mobility [WHO,2011]. Total bone mineral density, total body less head TBLH, lumbar bone mineral density (g/cm2) were measured through densitometry (Bishop et al, 2008). Statistical analysis: Independente t-test was used for comparing bone density between Type I (who could walk) and Type IV OI children (who moved using a wheelchair). A level of p ≤ .05 was taken as a significant one. RESULTS: Total bone mineral density (g/cm2] was significant higher among Type I OI children [0,759 ± 0,030(g/cm2] than among Type IV ones [0.619 ± 0.090 g/cm2]. There were no siginificant diferences in total body less head TBLH, and in lumbar spine bone mineral density g/cm2. CONCLUSION: Total bone mineral density was higher among OI children who could walk, suggesting the importance of physical activity (mobility) to bone health in children with Osteogenesis Imperfecta.