Abstract
Protein synthesis in the developing brain is higher than in adult brain (1) while the capillary density is lower (2). It thus seems probable that there is a difference in blood-brain amino acid transport across the blood-brain barrier mainly by three system: one system for large neutral amino acids (the system L), one system for basic amino acids, one system for acidic amino acids (3) and perhaps a fourth system for small neutral amino acids which is referred to as the ASC system (4). The ASC and acidic systems have a small activity and amino acids are mainly transported by the L and basic amino acid systems. The problem is, that if there is a high blood-brain transport of amino acids in young animals, does it come through a high transport of all amino acids or through specific modifications of some transport systems as seen in other tissues (5).
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