Abstract

Hypertension is one of the key risk factors for development of various forms of vascular disease including ischemic and hemorrlmgic stroke, coronary artery disease, and peripheral vascular disease. Blood pressure (BP) elevation and its treatment have implications for both primary ~md secondary prevention [1] and in the acute management of cardiovascular diseases. In acute myocardial infarction, administration of antihypertensive drugs, especially ~3-blockers and angiotensin-com~erting enzyme (ACE) inhibitors, are incorporated into the treatment algorithms [2-41. In patients with cerebrovascular events, best management strategies remain somewhat tmcertain. Contributing to this uncertainty are the heterogeneity of these conditions, complex interaction between systemic and cerebral circulation, differential involvement of vascular distributions, and limited data from clinical trials.

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