Abstract
Erythrocyte Sedimentation Rate testing (ESR) has long been used as a chronic inflammation marker. We evaluated the clinical usefulness of ESR with 20, 926 laboratory testing data obtained from a multiphasic health testing system. 1) ESR data were studied with 49 items of clinical chemistry, hematology and physiology. Only globulin and hemoglobin exhibited significant correlation (p>0.01) .2) ESR exhibited a negative correlation with MCV, but HGB did not. 3) The estimated multiple regressive equation was Y=-2.2546×hemoglobin value (g/dl) +9.6238×globulin value (g/dl) +15.7124. 4) Globulin increased with age but hemoglobin did not clearly decrease with it. 5) When the health testing data were applied to the estimation formula, 168/20, 926 (0.80%) were out of the -11mm area of the ESR regression line, and their showed hypochromic and microcytic in many cases. The results indicated that decreased hemoglobin means accelerated ESR but the anemia cases showing abnormally-low shape factors in MCV and MCH did not fit this assumption.
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