Abstract
Triterpenoid saponins and ginsenosides, the majority of which contain the aglycons protopanaxadiol or protopanaxatriol, are important biologically active compounds of Panax ginseng C. A. Meyer. The principal ginsenoside, the content of which in ginseng root is >20% of the total saponins, is Rb1 (1), which includes -sophorose and -gentiobiose residues (6-O-Dglucopyranosyl-D-glucose) in the C-3 and C-20 positions, respectively, of 20(S)-protopanaxadiol. The minor ginsenoside Rd (2) is a close structural analog of Rb1 and has a glucose instead of -gentiobiose in the C-20 position [1]. Rd has a broader spectrum of biological activity than Rb1, for example, it increases the differentiation of nerve stem cells, protects neurons from neurotoxic substances, and inhibits proliferation of HepG2 liver cancer cells [2]. However, the content of Rd in ginseng root is 4–5 times less than that of Rb1. Therefore, biotransformation of ginsenoside Rb1 into Rd, in particular by using microorganisms, is of practical importance [3].
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
