Abstract
EDITORIAL article Front. Comput. Neurosci., 07 May 2013 https://doi.org/10.3389/fncom.2013.00044
Highlights
Neuroscientists are becoming increasingly interested in modeling brain functions capturing underlying biophysical mechanisms requires plausible, biologically realistic models at the cellular level
The paper concludes that astrocytes support homeostatic regulation of network activity by modulating neural networks into a bistable regime of activity with two stable firing levels and spontaneous transitions between them
The comprehensive review article by Volman et al (2012) deals with the premise that pathways for astrocyte-neuron interaction can enhance the information processing capabilities of brains, yet in other circumstances may lead the brain on the road to pathological ruin
Summary
Neuroscientists are becoming increasingly interested in modeling brain functions capturing underlying biophysical mechanisms requires plausible, biologically realistic models at the cellular level. In the paper by Gordleeva et al (2012) the basic physiological functions of tripartite synapses and astrocytic regulation at the level of neural network activity is considered. The paper focuses on existing computational models of astrocytic involvement in epileptogenesis and their relevance to existing physiological data.
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