Abstract
Aims: Insect growth regulators (IGRs) offer alternatives to conventional chemical larvicides that pose problem of resistance and environmental safety. However, only a limited number of IGRs have been approved for use in mosquito control. The present investigation was to evaluate the insecticidal activity of a non -steroidal ecdysteroid agonist, methoxyfenozide (RH-2485), against last -instar larvae ofCuliseta morsitans (Culicidae: Diptera) under the laboratory conditions, and its effect on fecundity and fertility of females. Methodology: Based on preliminarybioassays, five concentrati ons ranging from 0.012 to 0.072mg/L were tested. The larvicidal test was made according to the World Health Organization(WHO) protocol standard by exposing newly ecdysed fourth -instar larvae for 24h. CL50value of methoxyfenozide value was determined by probit analysis. Results: The insecticidal activity of methoxyfenozide result in a dose - dependent reduction in adult emergence. In addition, larval mortality was relatively importan t compared with the mortality recorded for the other following developmental stages. The larval mortality varies betw een 16.84±3.89 % and 66.24±3.50 % for 0.012 mg/L and 0.072 OriginalResearch Article
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