Abstract
Marine sponges are well known as rich sources of biologically natural products. Growing evidence indicates that sponges harbor a wealth of microorganisms in their bodies, which are likely to be the true producers of bioactive secondary metabolites. In order to promote the study of natural product chemistry and explore the relationship between microorganisms and their sponge hosts, in this review, we give a comprehensive overview of the structures, sources, and activities of the 774 new marine natural products from sponge-derived microorganisms described over the last two decades from 1998 to 2017.
Highlights
The term “symbiosis” was first defined by the German mycologist Heinrich Anton de Bary in 1879 as “the living together of unlike organisms” [1]
This review comprehensively focuses on the chemical diversity and biological activity of the symbiotic microorganisms derived from different sponge species, covering 774 new compounds totally from 1998 to 2017
Two new compounds, designated JBIR 74–75 (1–2) (Figure 1), were isolated from the fungus Aspergillus sp. fS14, which was isolated from the unidentified marine sponge collected off Ishigaki Island, Okinawa, Japan
Summary
The term “symbiosis” was first defined by the German mycologist Heinrich Anton de Bary in 1879 as “the living together of unlike organisms” [1]. Symbiosis is an intimate and long-term biological interaction between two different biological organisms, whether reciprocal, symbiotic, or parasitic It is abundant and widespread in the sea for symbioses between microorganisms and marine organisms. Research on co-existing microorganisms derived from marine animals and plants has received increasing attention, especially sponge symbiotic microorganisms. In 2017, Fehmida Bibi et al [9] reviewed the latest studies on active secondary metabolites produced by sponge-derived commensal bacteria, suggesting that sponge symbiotic bacteria are one of the important sources of new drugs. This review comprehensively focuses on the chemical diversity and biological activity of the symbiotic microorganisms derived from different sponge species, covering 774 new compounds totally from 1998 to 2017
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
