Abstract
Abstract Cases presenting a problem of differentiation between latent syphilis and a chronic BFP reaction were collected, retested by the STS, and examined by the TPI test. Of 183 such cases studied, 39 (22.5 per cent) were negative by the TPI test. It is concluded that the incidence of BFP reactors, when screening of asymptomatic "seropositive" cases is performed with cardiolipin, is less than when such screening is done with other antigens. The Kolmer complement fixation test using cardiolipin antigen yielded fewer false positive reactions but lacked sufficient sensitivity to be used for exclusion purposes, due to the large proportion of latent syphilis which would be missed in such a procedure.
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