Abstract

Biogenic ZnO/MgO nanocomposite was synthesized using Ficus hispida bark extract. Diffraction patterns showed highly crystalline ZnO and MgO formation with hexagonal and cubic crystal structures. Zn-O, Zn-OH, and Mg-O vibrations authenticate the material formation with elongated rods as well as flakes-like morphologies. Optimal biocompatibility was observed from MCF-7 cell line and zebrafish model. ZnO/MgO nanocomposite showed effective anti-bactericidal activity against gram negative Klebsiella pneumonia, Escherichia coli and gram positive Staphlococcus aureus, Streptococcus mutans. There are no significant reports in ZnO/MgO with the reduction of Ficus hispida and similar materials are being used as dental cement and for other applications. Hence, this biogenic ZnO/MgO nanocomposite can be a preferable material for biomedical applications.

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