Bioengineered and biocompatible silver nanoparticles from Thalictrum foliolosum DC and their biomedical applications

Abstract

Bioengineered nanoparticles display unique characteristics at the cellular, atomic, and molecular levels with their geometric shapes dictating suitable actions and use. In the present study, bioengineered and bio-compatible silver nanoparticles (AgNPs) were obtained from Thalictrum foliolosum leaf extract which served as a capping and reducing agent. The effects of different parameters, such as varying concentrations of silver nitrate (0.2, 0.5, 1.0, and 2.0 mM), leaf extract (24.5, 24, 23.5, and 23 mL), pH (2, 4, 6, 7, and 8), and temperature (20, 40, 60, and 80 °C) were examined on the synthesis of T. foliolosum-assisted silver nanoparticles (TF@AgNPs) and their characterization accomplished by UV–visible and Fourier transform infrared spectroscopy, X-ray diffraction, Transmission, and Scanning electron microscopy, and Zeta potential analyses. X-ray and microscopy results revealed that TF@AgNPs were spherical with ~ 18.27 ± 3.9 nm size. The biological studies indicate potential antifungal, antioxidant, and anticancer properties besides hydrogen peroxide sensing, for the ensued TF@AgNPs suggesting their numerous biomedical appliances. A clean, cost-effective, and safer method for the procurement of bioengineered TF@AgNPs that precludes the use of any hazardous elements with no adverse effects is some additional sustainable attributes.