Abstract

Fresh leaf artichoke extracts contain high amounts of cynarin and related caffeoylquinic acids which possess high antioxidant activity. We have investigated mitochondrial stimulation and confirmed radical scavenging activity of cynarin, the lead compound of the special extract [15 – 30:1] from fresh leafs instead of dried material from Cynara cardunculus var. scolymus (L.) Benth., and its main bioactive metabolites caffeic acid, ferulic acid, dihydroferulic acid and their amide derivatives formed after administration of the fresh leaf artichoke extract to humans.

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