Abstract

856 Background: Malnutrition is a strong predictor of morbidity and mortality in advanced cancer. Accurate assessment of malnutrition is a significant challenge in cancer patients. Bioelectrical impedance analysis (BIA) is a safe, simple, non-invasive and objective technique that is increasingly being used to evaluate nutritional status and changes in body composition in cancer. BIA measures resistance and reactance to the flow of a constant alternating electric current to a living organism, which in turn is used to calculate phase angle, a measure of cellular health and integrity. We investigated if BIA-derived phase angle could assess nutritional status as measured by Subjective Global Assessment (SGA) in advanced breast cancer. Methods: We evaluated a case series of 79 histologically confirmed stage III-IV breast cancer patients treated at Cancer Treatment Centers of America at Midwestern Regional Medical Center between January 2000 and July 2003. A Kruskal-Wallis (KW) test - owing to nonnormal distrib...

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