Biocompatible superhydrophobic surface on Zr-based bulk metallic glass: Fabrication, characterization, and biocompatibility investigations

Abstract

Superhydrophobic metal materials are promising candidates for preparing the precision blood-contacting medical devices. Finding a metal material with excellent biocompatibility and superplastic forming ability to fabricate superhydrophobic surface is of great practical significance. Zr-based bulk metallic glass with high glass-forming ability was selected as the experimental sample. Micro-nano hierarchical structure was etched by electrochemical method in the ultrasonic environment, and the superhydrophobic surface with good biocompatibility was obtained after further modification. Electrochemical polarization tests show that the superhydrophobic surface can maintain long-term corrosion resistance in simulated body fluids. Blood and cell tests indicate that the superhydrophobic sample has an extremely rate of hemolysis and exhibits the ability to effectively inhibit the adhesion of platelets and smooth muscle cells. In addition, the superhydrophobic sample surface also exhibits good mechanical durability and chemical stability. This study offers a new perspective on the application of Zr-based bulk metallic glass in blood-contacting medical devices.