Biocompatible Coatings for Medical Applications

Abstract

Biocompatible coatings have become increasingly pivotal across various industries, particularly in biomedical fields, due to their ability to minimize inflammation, deter bacterial adhesion, and foster tissue integration. They offer a protective and compatible barrier, enhancing the safety and efficacy of medical procedures, especially in addressing complex cases. As demand rises for implantable medical devices and drug delivery systems, polymer matrices featuring copolymers, blends, ceramics, and nanocomposites with antiproliferative drug components are gaining prominence for seamless integration into the body. Amid the global surge in medical implants, biocompatible coatings present vast opportunities for exploration, aiming to mitigate issues like infection, blood clots, and tissue integration linked to drug toxicity and blood-contacting implants. This chapter encompasses the current state of biocompatible coatings in medical devices, spanning orthopedic, cardiovascular, dental, ophthalmic, and diagnostic applications, along with their constraints and future prospects. It delves into surface modifications, both physical and chemical, with a biomimetic focus, addressing hurdles and cutting-edge technologies in developing biocompatible materials. Through organized presentation, this article aims to streamline ongoing research and bolster innovation toward enhanced patient satisfaction in medical applications.