Abstract
Indonesian forests are one of the richest ecosystems in the world. Secondary metabolites with molecular structures and various biological activities of medicinal plant extracts have excellent potential to be developed into medicines of various diseases. Phenolic compounds found in plants have many biological effects including antioxidants and antimicrobials. Secondary metabolite compounds play a protective role against damage caused by disease. Traditional medicine and treatment among the people of Kutai Kartanegara is very diverse and has been widely used. Type of Tapak Leman (Hippobroma longiflora (L) G. Don) is one type of forest plants have been used as a medicinal plant by Ethnic Kutai with the efficacy of treatment of kidney stones and increase of stamina or vitality. The aim of study is to investigate the biological activity of Tapak Leman forest type that had been used as medicine. The leaves of the plant samples were extracted using ethanol and then extracts tested phytochemical content, toxicity, biological activity of antioxidant and antimicrobial. Testing of antioxidant activity by spectrophotometric method using DPPH (1,1-diphenyl-2-picrylhydrazyl), the level of toxicity using by BSLT (Brine Shrimp Lethality Test), and antimicrobials by diffusion method. The results showed is Tapak Leman type has a phytochemical content of alkaloids, flavonoids, tannins, saponis and steroids. Type of Tapak Leman properties is toxic, has strong antioxidant and strong on fungi.
Highlights
Forests in Indonesia are one of the ecosystems that have the largest species richness in the world
Testing of antioxidant activity by spectrophotometric method using diphenyl-2-picrylhydrazyl radical (DPPH) (1,1-diphenyl-2picrylhydrazyl), the level of toxicity using by BSLT (Brine Shrimp Lethality Test), and antimicrobials by diffusion method
The purpose of this study was to identify the bioactivity of medicinal plants from forest plants that have been traditionally used by the Kutai people by looking at phytochemical content, toxicity, antioxidant antimicrobial activity
Summary
Forests in Indonesia are one of the ecosystems that have the largest species richness in the world. Indonesian forests contain more than 400 species of trees of high economic value and approximately 25,000 species of flowering plants [1]. The development of new types of diseases has increased from year to year, and many drugs currently circulating are no longer able to cope with these new diseases. The search for new types of drugs still continues at any time [2]. Plant ingredients contain various forms of antioxidants. Phenolic compounds are found in plants, have many biological effects. Flavonoids and other phenolics play a protective role against damage caused by disease [3, 4]. Secondary metabolites with diverse molecular structures and biological activities derived from medicinal plant forest extracts have excellent potential to be developed into various diseases. The level of herbal production in general is still
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