Abstract

Diorganotin(IV) and diorganosilicon(IV) derivatives of the types R2MCl(TSCZ) and R2M(TSCZ)2 (where TSCZ is the anion of a thiosemicarbazone ligand, R=Ph or Me and M=Sn or Si) have been synthesized and characterized by elemental analyses, molecular weight determinations and conductivity measurements. The mode of bonding has been established on the basis of IR and 1H, 13C 29Si and 119Sn NMR spectroscopic studies. Some of the representative complexes have also been evaluated for their antimicrobial effects on different species of pathogenic fungi and bacteria in vivoas well as in vitro.The results of these investigations are reported. © 1998 John Wiley & Sons, Ltd.

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