Abstract
The genus Zingiber consists of about 85 species and many of these species are used as food, spices, and medicines. One of the species, Zingiber montanum (J. Koenig) Link ex A. Dietr. is native to Southeast Asia and has been extensively used as traditional medicines and food. The aim of this review was to collect and critically analyze the scientific information about the bioactive compounds and pharmacological activities of Z. montanum with focus on one of the main components, zerumbone (ZER). Various studies have reported the analysis of volatile constituents of the essential oils from Z. montanum. Similarly, many phenylbutanoids, flavonoids and terpenes were also isolated from rhizomes. These essential oils, extracts and compounds showed potent antimicrobial, anti-inflammatory and antioxidant activities among others. Zerumbone has been studied widely for its anticancer, anti-inflammatory, and other pharmacological activities. Future studies should focus on the exploration of various pharmacological activities of other compounds including phenylbutanoids and flavonoids. Bioassay guided isolation may result in the separation of other active components from the extracts. Z. montanum could be a promising source for the development of pharmaceutical products and functional foods.
Highlights
The Zingiberaceae family consists of about 50 genera and more than 1500 species which are distributed all over the world and most of them are found in Asia, CentralAppl
ZER selectively inhibited the proliferation of human cervical cancer cells (HeLa) cells and enhanced the anti-proliferative activity of anticancer agents vinblastine and paclitaxel
ZER exerted anticancer effects against hormone refractory DU145 prostate cancer cells mediated through the inhibition of aberrant signaling axis of IL-6/JAK2/STAT3
Summary
The Zingiberaceae family consists of about 50 genera and more than 1500 species which are distributed all over the world and most of them are found in Asia, Central. Plants belonging to various genera of Zingiberaceae family are used Appl. 11, 10205 food, spice and medicines in many parts of the world [1]. One of the must studied gen-2 of 24 era of this family, Zingiber consists of about 85 species [2] and Zingiber officinale Roscoe. Is the most commonly cultivated and used species.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
