Abstract
Histoplasmosis is a deep fungal infection caused by Histoplasma capsulatum. It presents commonly with transient pulmonary infection but disseminated form can involve any system in the body. Adrenal gland is affected frequently in histoplasmosis but bilateral involvement is unusual. Adrenal histoplasmosis is also common in immunocompromised host. We report a case of bilateral adrenal histoplasmosis in an immunocompetent patient without any features of adrenal insufficiency. Histoplasmosis was diagnosed by fine needle aspiration cytology (FNAC) from adrenal gland. Patient was treated with itraconazole with good response and is currently under follow-up.
Highlights
Histoplasmosis is a fungal infection caused by a dimorphic saprophytic fungus Histoplasma capsulatum [1]
We report a case of bilateral adrenal mass in an immunocompetent patient who presented with non-specific symptoms and responded well to antifungal treatment
A 32-year-old male cultivator presented with low grade intermittent fever, weight loss and anorexia for one and a half years. He lost around 10 kg body weight during his period. He was diagnosed as a case of tuberculosis on the basis of his clinical features and few investigation reports about fourteen months back and antitubercular treatment was started, but the patient discontinued treatment as there was no improvement
Summary
Histoplasmosis is a fungal infection caused by a dimorphic saprophytic fungus Histoplasma capsulatum [1] It is endemic in various part of the world especially in North and Latin America, south of Sahara and sporadic in Africa and Far-East Asia [2,3,4,5]. It is found as a mycelium form in the soil mixed with bat and bird droppings. Histoplasma causes a spectrum of illness from subclinical infection to progressive disseminated disease Though it affects immunocompromised people mostly, there are several reports of infections in immunocompetent persons [6,7]. We report a case of bilateral adrenal mass in an immunocompetent patient who presented with non-specific symptoms and responded well to antifungal treatment
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
