Abstract
Tidy et al showed that 1/3 of all referrals for colposcopy, in settings where primary high-risk HPV (HR-HPV) test is used for screening, are due to persistently positive tests with a negative triage cytology (BJOG 2020 xxxx). These represent a significant burden for colposcopists but yielding a relatively low number of cases of CIN2+ (7%), thus translating to a low positive predictive value (PPV) for this approach.
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